Utilising inorganic nanocarriers for gene delivery.

نویسندگان

  • Xian Jun Loh
  • Tung-Chun Lee
  • Qingqing Dou
  • G Roshan Deen
چکیده

The delivery of genetic materials into cells to elicit cellular responses has been extensively studied by biomaterials scientists globally. Many materials such as lipids, peptides, viruses, synthetically modified cationic polymers and certain inorganic nanomaterials could be used to complex the negatively charged plasmids and deliver the formed package into cells. The recent literature on the delivery of genetic materials utilising inorganic nanoparticles is carefully examined in this review. We have picked out the most relevant references and concisely summarised the findings with illustrated examples. We further propose alternative approaches and suggest future pathways towards the practical use of multifunctional nanocarriers.

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عنوان ژورنال:
  • Biomaterials science

دوره 4 1  شماره 

صفحات  -

تاریخ انتشار 2016